Prevalence of impaired odor identification in Parkinson disease with imaging evidence of nigrostriatal denervation.

Associated faculty or student(s): Publication Date:
Friday, April 1, 2016
Abstract:

There is wide variability in the reported prevalence rates of abnormal smell in Parkinson disease (PD). This study assessed the prevalence of abnormal smell, using the University of Pennsylvania Smell Identification Test (UPSIT), in 183 patients with PD with confirmed PET imagingevidence of nigrostriatal denervationImpaired olfaction in this sample was nearly universal (97.8 %). Wide-ranging prior olfactory impairment estimates may reflect not only uncertainty regarding diagnostic classification, but also the use of inaccurate normative data and differences in olfactory tests used.

KEYWORDS:

Aging; Dopa

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