Inactivation of Prefrontal Cortex Delays Emergence from Sevoflurane Anesthesia

Associated faculty or student(s): Publication Date:
Thursday, June 10, 2021
Abstract:

Inactivation of Prefrontal Cortex Delays Emergence from Sevoflurane Anesthesia

Studies aimed at investigating brain regions involved in arousal state control have been traditionally limited to subcortical structures. In the current study, we tested the hypothesis that inactivation of prefrontal cortex, but not two subregions within parietal cortex—somatosensory barrel field and medial/lateral parietal association area—would suppress arousal, as measured by an increase in anesthetic sensitivity. 

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